hrp0086rfc9.8 | Pathophysiology of Disorders of Insulin Secretion | ESPE2016

Micro RNA and Diabetic Nephropathy

Abdelghaffar Shereen , Elmougi Fatma , Abdelaty Sahar , Elshiwy Yasmin , Elsayed Reham , Abdelrahman Heba , Mehawed Hend , Elgebaly Heba , Ahmed Sakinatalfouad , Elalfy Peter

Background: MicroRNAs (miRNAs) are short non-coding RNAs that repress target gene expression via post-transcriptional mechanisms.Objective and hypotheses: To study the expression of miRNA-25, miRNA-216, miRNA-21, miRNA-93, miRNA-377 in a sample of 100 type 1 diabetic patients with and without microalbuminuria to probe their role in development of diabetic nephropathy.Methods: Hundred type 1 diabetic patients, 50 with microalbuminur...